Specialized luciferase substrates and vectors enable easy, noninvasive bioluminescence imaging in small animals that improves biological relevance.
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Follow cells of interest in vivo
cells of interest
Mouse with luciferase transgene
stably transfect with luciferase construct
Monitor genetic elements and activation in vivo
pGL4 Vectors
Firefly substrates Renilla substrates
inject cells
inject luciferase substrates
Workflow tools
pGL4 Luciferase Reporter Vectors
VivoGlo™ In Vivo Imaging Substrates NEW! EnduRen™ In Vivo Renilla Luciferase Substrate ViviRen™ In Vivo Renilla Luciferase Substrate
Learn more about in vivo imaging with bioluminescence from these articles:
Identification of apoptotic cells in living reporter mice using modified luciferin Imaging with luciferase in whole animals Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer In vivo evaluation of regulatory sequences Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVDaminoluciferin
8901TA
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Promega Australia - Monthly online Magazine - March 2010 edition Lees publicatie 2Home