Training n the lab Upcoming Webinar Learn about basic concepts, tips and techniques to help with your research. Learn how products are designed and how to use them in your lab. Attendees have an opportunity to interact with a Technical Service Scientist directly during the scheduled presentation via chat. Tuesday, January 12, 2016 Understanding the Role of the Inflammasome in Inflammation Presented by Martha O’Brien, PhD The inflammasome is a multiprotein complex expressed in myeloid cells there is responsible for activation of inflammatory processes as part of the innate immune system. The inflammasome complex contains different proteins depending on the initiating event, but central to the inflammatory process is activation of caspase-1, which in turn activates the cytokines interleukin-1ß and interleukin-18 by proteolytic cleavage of the pro-forms of these molecules. We recently developed a bioluminescent assay for the rapid detection of caspase-1 that enables direct measurement of an upstream signaling event in the process of inflammation. We will discuss in detail the specificity of this novel assay, monitoring caspase-1 in cells and released into the medium, differences between cell types, and multiplexing with other assays to measure relevant activities, such as cell death and IL-1ß release. Webinars are FREE, though we ask you to register. Registration allows us to send you the link for the webinar. and Registration Information enews | January 2016 Pagina 8
Pagina 10Interactieve online nieuwsbrief, deze PDF of uitgave is levensecht online geplaatst met Online Touch en bied het van papier naar online converteren van digi lesmateriaal.
Promega Biotech AB - Monthly online Magazine - January 2016 edition Lees publicatie 10Home